Just some notes on WCIV DVD:
Yes, it has more "cleaner" cut scenes and audio due to the DVD format.
And yes, it can run on drives other than the creative encore drives, but it depends on your system setup.
One other main difference though is the cut scenes. You may notice, the audio is slightly different (you'll hear certain dialogue that was subdued in the background in CD version at the forefront in the DVD version and vice versa) and,
there are certain camera angles that are changed during the cutscenes and often extra seconds of "deleted footage" added to these cutscenes. (I know a few extra seconds doesn't really matter, but it is noticeable, especially during the opening cutscene.)
And one more thing, I have not found it too be compatible with Windows XP, but does run on both versions of Win98 and ME.